Professor Douglas Easton

Douglas Easton

University position

Professor

Professor Douglas Easton is pleased to consider applications from prospective PhD students.

Departments

Department of Oncology and Department of Public Health and Primary Care

Institutes

Strangeways Research Laboratory

Email

douglas@srl.cam.ac.uk

Home page

http://www.srl.cam.ac.uk/gene...

Research Themes

Epidemiology

Cancer genomics

Interests

My main research area is genetic susceptibility to cancer, with particular emphasis on breast and prostate cancer. I also have particular interests in the genetic epidemiology of BRCA1 and BRCA2, intermediate markers of cancer risk (such as breast density), and in the development of statistical methods. A recent focus of my group has been large-scale association studies to identify moderate risk cancer susceptibillity variants. We co-ordinate international consortia conducting association studies in breast (BCAC) and prostate cancer (PRACTICAL), and in BRCA1/2 carriers.

Research Focus

Keywords

association studies

statistical genetics

BRCA1

BRCA2

breast density

Cancer sites

breast

melanoma

ovary

prostate

testis

uterus and unspecified

Equipment

Bioinformatics

DNA sequencing

Epidemiology

Genomics

High-throughput genotyping

PCR

Public health

Statistical analysis

Key publications

Easton DF et al (2007), “Genome-wide association study identifies novel breast cancer susceptibility loci”, Nature 447(7148):1087–93

Eeles RA et al (2008), “Identification of multiple novel prostate cancer susceptibility loci by a genome-wide association study”, Nature Genet 40(3):316–21

Antoniou et al (2008), “Common breast cancer predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers”, Am J Hum Genet 82(4):937–48

Collaborators

Cambridge

Alison Dunning

Paul Pharoah

Bruce Ponder

Ruth Warren

United Kingdom

Rosalind Eeles Web: http://www.icr.ac.uk/research...

Gareth Evans Web: http://www.breastcentre.manch...

Michael Stratton Web: http://www.sanger.ac.uk/resea...

International

Georgia Chenevix-Trench Web: http://www.qimr.edu.au/

Fergus Couch Web: http://www.mayoclinic.org/bio...

Graham Giles Web: http://www.cancervic.org.au/a...

Per Hall Web: http://ki.se/ki/jsp/polopoly....

John Hopper Web: http://www.dph.unimelb.edu.au...