Dr David Sargan
Dr David Sargan is pleased to consider applications from prospective PhD students.
http://www.vet.cam.ac.uk/rese... (personal home page)
Basic biology (model organisms)
My lab is using genomic mapping techniques to identify genes associated with breed specific predispositions to particular cancers in dogs. Current projects are histiocytic sarcoma in flat coated retrievers, splenic haemangisosarcoma in German shepherd dogs and adenocarcinoma in cocker spaniels. We are also applying cytogenetic analyses to the same tumours.
Sargan DR, Aguirre-Hernandez J, Galibert F and Ostrander EO. (2007) An extended microsatellite set for linkage mapping in the domestic dog. J Heredity 98:221–31
Sargan DR, Milne BS, Aguirre Hernandez J, O’Brien PCM, Malcolm A Ferguson-Smith MA, Tess Hoather T and Dobson JM (2005), “Chromosome rearrangements in canine fibrosarcomas”, J Heredity 96:766–773
Milne BS, Hoather T, O’Brien PCM, Yang F, Ferguson-Smith MA, Dobson J, Sargan DR (2004), “Karyotype of canine soft tissue sarcomas: a multi-colour, multi-species approach to canine chromosome painting”, Chromosome Res 12:825–835
No collaborators listed